This is the report of the Western Australian Coroner’s inquest into the deaths of 22 Aboriginal people around Fitzroy Crossing in 2006. The inquest was held to explore the reasons for a large number of deaths of Aboriginal persons in the Kimberley whose deaths appeared to have been caused or contributed to by alcohol abuse or cannabis use and also, if possible, to identify reasons for an alarming increase in suicide rates. Evidence was heard from the families of the deceased, Aboriginal groups, government agencies and residents of several towns the Coroner toured during his inquiry. The inquest revealed that there is no real leadership or coordination in the response to the disaster of Aboriginal living conditions in the Kimberley on the part of either the State or Commonwealth governments. The coroner found that most of the deaths were alcohol- and drug-related, and 27 recommendations were made in his report suggesting a range of actions which could be taken to address these issues. The report also explores the circumstances of the individual tragedies of the 22 deaths.